Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study

Compared to twice-weekly surveillance, once-weekly microbiological surveillance reduces costs by 30% with 6% loss in clinically relevant PPM detections. No surveillance reduces costs by 60% with 14% detection loss.

Authors

Valentijn A. Schweitzer (ORCID: https://orcid.org/0000-0001-9640-7291)
Jelle L G Haitsma Mulier (ORCID: https://orcid.org/0000-0002-3035-0736)
Olaf L. Cremer (ORCID: https://orcid.org/0000-0003-4264-1108)
Marc J. M. Bonten
Lennie P. G. Derde (ORCID: https://orcid.org/0000-0002-3577-5629)
Fleur J van Dijk

Institutions

University Medical Center Utrecht (NL)
Europeana Foundation (NL)

Publication Details

Journal: Critical Care
Published: 2025-06-17
DOI: https://doi.org/10.1186/s13054-025-05494-5
Citations: 2
Primary Topic: Nosocomial Infections in ICU
Type: article
Field-Weighted Citation Impact: 3.09

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article

Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study

Valentijn A. Schweitzer, Jelle L G Haitsma Mulier, Olaf L. Cremer, Marc J. M. Bonten et al.

Jun 17, 2025

2 citations

Critical Care

Nosocomial Infections in ICU

3.09

article

Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study

Valentijn A. Schweitzer, Jelle L G Haitsma Mulier, Olaf L. Cremer, Marc J. M. Bonten, Lennie P. G. Derde, Fleur J van Dijk

June 17, 2025article en

2 citations

Abstract

Compared to twice-weekly surveillance, once-weekly microbiological surveillance reduces costs by 30% with 6% loss in clinically relevant PPM detections. No surveillance reduces costs by 60% with 14% detection loss.

Critical CareVol. 29(1)

University Medical Center Utrecht (NL), Europeana Foundation (NL)

Good health and well-being

Openalex Percentile: Top 9%

Nosocomial Infections in ICU

3.09

DOI Open Access PDF OpenAlex

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Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study — Valentijn A. Schweitzer, Jelle L G Haitsma Mulier, et al. · Critical Care (2025) | TGRS Research Map | TGRS