Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma
PSMD12 emerges as a crucial gene in promoting BM, potentially serving as an early warning indicator of BM in early-stage LUAD. The upstream regulatory network of PSMD12 overexpression provides potential mechanisms for BM in LUAD patients.
Authors
- Wenbin Jiang (ORCID: https://orcid.org/0009-0004-8559-2734)
- Jiaxing Deng (ORCID: https://orcid.org/0009-0001-6233-9566)
- Lishuang Qi (ORCID: https://orcid.org/0000-0002-2991-6544)
- Juxuan Zhang
- Lefan Tang
- Z. Wang (ORCID: https://orcid.org/0009-0000-4306-2373)
- Wenyuan Zhao
- Hao Li (ORCID: https://orcid.org/0000-0002-5462-8974)
- Xin Li (ORCID: https://orcid.org/0000-0002-7414-5734)
- Yixin Liu (ORCID: https://orcid.org/0000-0001-5295-3098)
- Meng Zhang (ORCID: https://orcid.org/0000-0003-3643-9501)
- Shilong Liu (ORCID: https://orcid.org/0000-0001-7821-9721)
- Yan Yu (ORCID: https://orcid.org/0000-0001-5598-763X)
- Run-Zhi Wang
- Dexin Jia
Institutions
- Harbin Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1186/s12967-025-06680-3
- Citations
- 3
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- Harbin Medical University
- National Natural Science Foundation of China