Clinical Significance of <i>TP53</i> -Mutant Clonal Hematopoiesis Across Diseases
TP53-CHIP contributed to a wide range of outcomes besides myeloid neoplasm mortality. TP53-CHIP, when combined with environmental factors, showed a remarkably higher risk for disease-specific mortality, accompanied by excess risks.
Authors
- Yukihide Momozawa (ORCID: https://orcid.org/0000-0001-5638-3504)
- Yoshiaki Usui (ORCID: https://orcid.org/0000-0001-6180-0704)
- Koichi Matsuda (ORCID: https://orcid.org/0000-0001-7292-2686)
- Hidewaki Nakagawa (ORCID: https://orcid.org/0000-0003-1807-772X)
- Hanae Iijima
- Yusuke Iwasaki (ORCID: https://orcid.org/0009-0002-8576-1775)
- Mikiko Endo
Institutions
- RIKEN Center for Integrative Medical Sciences (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Blood Cancer Discovery
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1158/2643-3230.bcd-24-0355
- Citations
- 3
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 5.31
Funders
- Takeda Science Foundation
- Japan Agency for Medical Research and Development
- Yasuda Memorial Medical Foundation
- RIKEN