Physiological Control of Realheart Total Artificial Heart
The physiological control system demonstrated its ability to adapt to rapid transitions between physiological states, although occasional undershoots in pressure were observed during transitions from exercise to rest conditions. This study highlights the Realheart TAH's ability to autonomously adjust to varying physiological conditions and patient needs, showing promise for treating patients with advanced HF. Future work will focus on optimizing the control system to further enhance the device's responsiveness and stability during rapid physiological transitions.
Authors
- Michael Broomé (ORCID: https://orcid.org/0000-0002-8987-9909)
- Thomas Finocchiaro (ORCID: https://orcid.org/0000-0002-2722-0260)
- D. Jonasson
- Shaikh Faisal Zaman (ORCID: https://orcid.org/0000-0002-3144-3176)
- Nils Brynedal Ignell
- Emanuele Perra (ORCID: https://orcid.org/0000-0002-7432-2139)
- Seraina A. Dual (ORCID: https://orcid.org/0000-0001-6867-8270)
- Ina Laura Perkins (ORCID: https://orcid.org/0000-0003-2521-4171)
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Artificial Organs
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1111/aor.15036
- Citations
- 1
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- VINNOVA
- Energimyndigheten