sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models
Our studies establish a better mouse model for FTLD-GRN and uncover novel pathways modifying PGRN deficiency phenotypes.
Authors
- Fenghua Hu (ORCID: https://orcid.org/0000-0002-6447-9992)
- Marcus B. Smolka (ORCID: https://orcid.org/0000-0001-9952-2885)
- Ling Hao (ORCID: https://orcid.org/0000-0002-0106-5266)
- Weizhi Yu
- Jeremy M. Baskin (ORCID: https://orcid.org/0000-0003-2939-3138)
- Masaaki Uematsu (ORCID: https://orcid.org/0000-0002-0197-8401)
- Gwang Bin Lee (ORCID: https://orcid.org/0000-0003-4756-0921)
- Weiguo He (ORCID: https://orcid.org/0000-0003-2143-3748)
- Cha Yang
- Étienne Doré (ORCID: https://orcid.org/0000-0002-2347-5012)
- Ethan J. Sanford (ORCID: https://orcid.org/0000-0003-0722-3058)
- Huan Du (ORCID: https://orcid.org/0000-0003-0728-7844)
- Éric Boilard
Institutions
- Cornell University (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Molecular Neurodegeneration
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1186/s13024-025-00863-8
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Institute of Neurological Disorders and Stroke