A single-cell plume transcriptome atlas of the cold-seep tubeworm Paraescarpia echinospica
Vestimentiferan tubeworms are representative species in deep-sea chemosynthetic ecosystems. Unlike most animals, these invertebrates lack mouths and digestive systems. Instead, their plumes function as the primary organ for direct metabolic exchange with the environment. Here, we present the single-cell transcriptome atlas of the Paraescarpia echinospica plume, offering single-cell resolution analysis for a deep-sea tubeworm. Our analysis revealed six cell clusters, namely hemocytes, proliferative cells, muscle cells, epithelial cells, nerve1 cells, and nerve2 cells, and we further characterized genes associated with immunity and transport. These findings establish a crucial foundation for future single-cell studies of tubeworms.
Authors
- Yunlu Xiao (ORCID: https://orcid.org/0009-0005-9787-033X)
- Ximeng Dong
- Qianyue Ji (ORCID: https://orcid.org/0000-0001-9311-360X)
- Guangyi Fan (ORCID: https://orcid.org/0000-0001-7365-1590)
- Jie Ma (ORCID: https://orcid.org/0000-0003-2403-606X)
- Haibin Zhang (ORCID: https://orcid.org/0000-0003-4086-3823)
- Shanshan Liu (ORCID: https://orcid.org/0000-0002-5756-1728)
- Zhe Zhang (ORCID: https://orcid.org/0000-0003-3983-1226)
- Nannan Zhang (ORCID: https://orcid.org/0000-0002-8192-7718)
- Xianghui Zhang (ORCID: https://orcid.org/0000-0002-6709-6073)
- Yingying Zhang (ORCID: https://orcid.org/0000-0003-3819-5467)
- Hongxi Chen (ORCID: https://orcid.org/0009-0002-1622-4861)
- Liang Meng (ORCID: https://orcid.org/0000-0003-4129-7691)
- Weijia Zhang
- Zhen Cui
Institutions
- BGI Group (China) (CN)
- Chinese Academy of Sciences (CN)
- Sanya University (CN)
- Institute of Deep-Sea Science and Engineering (CN)
- BGI Research (CN)
Publication Details
- Journal
- Scientific Data
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1038/s41597-025-05392-z
- Citations
- 1
- Primary Topic
- Ocean Acidification Effects and Responses
- Type
- article
- Field-Weighted Citation Impact
- 1.79