Investigation of the Preventive Effect of Quercetin on 5-Fluorouracil Toxicity

The authors concluded that quercetin prevents 5-fluorouracil-induced nephrotoxicity by comparing the scores of the histologic changes in kidney tissue of the 2 groups using parameters such as inflammatory cell infiltration, tubular degeneration, glomerular degeneration, glomerular atrophy, edema, and congestion. Further studies should be performed to clarify the dosage and usage schedule.