Linking Comorbidity and Inflammation: The Role of Comorbidity Polypharmacy Score in Chronic Limb-Threatening Ischemia
Higher CPPS is associated with elevated inflammatory markers and declining hemoglobin, suggesting that multimorbidity and polypharmacy contribute directly to systemic inflammation. CPPS, alongside NLR, PLR, and SII, may support risk stratification and personalized management in CLTI patients.
Authors
- G Galzerano (ORCID: https://orcid.org/0000-0002-4073-9577)
- Gianmarco de Donato (ORCID: https://orcid.org/0000-0003-2451-8501)
- Giulia Casilli
- Edoardo Pasqui (ORCID: https://orcid.org/0000-0001-6619-0159)
- Tommaso Anichini
- Eleonora Cerbini
- Leonardo Pasquetti
Institutions
- University of Siena (IT)
Publication Details
- Journal
- Annals of Vascular Surgery
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1016/j.avsg.2025.05.051
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00