MiR-106b-5p, MiR-200c-3p, and MiR-146a-5p expression as putative biomarkers for disease state in primary immune thrombocytopenia
MiR-106b-5p and miR-200c-3p were elevated, while miR-146a-5p was suppressed in ITP versus controls. Reduced miR-106b-5p indicated a full response to therapy. These markers may be useful as diagnostic ITP biomarkers. Moreover, miR-106b-5p level can be used to monitor response to therapy and as a predictor for complete response.
Authors
- Mahmoud A. El‐Hawy (ORCID: https://orcid.org/0000-0002-3420-922X)
- Reham S. El Zaiat
- Mai A. H. Abouelenin
- Amany A. Saleh
- Manal Monir Mansour (ORCID: https://orcid.org/0000-0003-2532-7539)
- Iman A. Ahmedy (ORCID: https://orcid.org/0000-0003-0816-3050)
Institutions
- Taibah University (SA)
- Menoufia University (EG)
Publication Details
- Journal
- Expert Review of Hematology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1080/17474086.2025.2522298
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00