Synchronous Bladder Metastasis From Chromophobe Renal Cell Carcinoma: A Report of a Rare Case

Renal cell carcinoma (RCC) is the most frequent form of kidney cancer and represents a small percentage of all adult cancers. Metastasis of RCC to the bladder is exceptionally uncommon, with only a limited number of cases documented, the majority being of the clear cell subtype. Instances involving the chromophobe variant are particularly rare. We report the case of a 29-year-old female presenting with anemia, gross hematuria, and left flank pain. Abdominal computed tomography (CT) revealed a left renal mass with features suggestive of a perinephric abscess, along with a bladder lesion. Cystoscopy with transurethral resection of the bladder tumor (TURBT) and percutaneous drainage of the abscess were performed, followed by left radical nephrectomy. Histopathological examination of both renal and bladder specimens confirmed the eosinophilic variant of chromophobe RCC (chRCC). A partial cystectomy was subsequently performed, achieving R0 resection. This case highlights an unusual metastatic pattern of chRCC and underscores the importance of aggressive surgical management in selected patients.