Molecular Insights into Outer Dynein Arm Defects in Primary Ciliary Dyskinesia: Involvement of ZMYND10 and GRP78
The altered expression of DNAH5, ZMYND10, and GRP78, along with metabolic shifts, points to a complex link between ciliary dysfunction and cellular stress in PCD. Further studies are needed to clarify the underlying mechanisms.
Authors
- Elif Karakoç (ORCID: https://orcid.org/0000-0002-0677-1047)
- Emirhan Nemutlu (ORCID: https://orcid.org/0000-0002-7337-6215)
- Halime Nayır Büyükşahin (ORCID: https://orcid.org/0000-0002-6909-7993)
- Pergin Atilla (ORCID: https://orcid.org/0000-0001-5132-0002)
- Nagehan Emiralioğlu (ORCID: https://orcid.org/0000-0002-1405-8401)
- Zeynep Bengisu Kaya (ORCID: https://orcid.org/0000-0001-9713-8732)
- Cemil Can Eylem (ORCID: https://orcid.org/0000-0002-3353-2869)
- Uğur Özçelik (ORCID: https://orcid.org/0000-0003-1587-5216)
- Alyssa B. Danis
- İlker Levent Erdem (ORCID: https://orcid.org/0000-0001-5931-4408)
Institutions
- Mayo Clinic in Florida (US)
- University at Buffalo, State University of New York (US)
- Hacettepe University (TR)
Publication Details
- Journal
- Cells
- Published
- 2025-06-17
- DOI
- https://doi.org/10.3390/cells14120916
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hacettepe Üniversitesi