Synthesis and characterization of 2,4,6-trihydroxy benzophenone and its activity as sunscreen
Benzophenone was synthesized through a condensation reaction of benzoic acid and phloroglucinol with an Eaton reagent as a catalyst. The percentage of the product was 60%, and it was characterized using FTIR and 1H-NMR. The sunscreen activity was carried out using a UV-Vis spectrophotometer to calculate the SPF value. The synthesis result was made in several concentration variations: 100, 150, 200, 250, and 300 ppm to measure the SPF values. The results showed that the SPF values were 9.89, 13.39, 17.83, 23.77, and 28.26, respectively. Based on this, it can be concluded that these compounds have biological activity as sunscreen and samples of 200-300 ppm are included in the ultra-category as sunscreen.
Authors
- Ni Komang Tri Dharmayani (ORCID: https://orcid.org/0000-0002-3427-0821)
- Emmy Yuanita (ORCID: https://orcid.org/0000-0003-1610-7200)
- Ima Arum Lestarini (ORCID: https://orcid.org/0009-0009-3375-0995)
- Baiq Nila Sari Ningsih (ORCID: https://orcid.org/0000-0001-6893-2195)
- Sudirman Sudirman
- Maria Ulfa (ORCID: https://orcid.org/0000-0002-0071-7218)
- Ainni Rohmana
Institutions
- University of Mataram (ID)
- University of North Carolina at Greensboro (US)
Publication Details
- Journal
- Acta Chimica Asiana
- Published
- 2025-05-31
- DOI
- https://doi.org/10.29303/aca.v8i1.175
- Primary Topic
- Diverse Scientific Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00