Clinical Outcomes of Patients with SLE Treated with Belimumab, Without Versus With Prior Immunosuppressant Use: a US Claims Database Study
In this large, retrospective, real-word study using IPTW adjustment, initiating belimumab without prior IS use was associated with OGC-sparing benefits and reduced incidence and severity of SLE flares.
Authors
- Sung Sam Lim (ORCID: https://orcid.org/0000-0003-2361-0787)
- Kwong-Wai Man (ORCID: https://orcid.org/0000-0001-6382-5219)
- Bernard Rubin (ORCID: https://orcid.org/0000-0002-9250-3865)
- Karen Worley (ORCID: https://orcid.org/0009-0002-0952-8883)
- Maral DerSarkissian (ORCID: https://orcid.org/0000-0002-5528-6531)
- Brendan Rabideau (ORCID: https://orcid.org/0000-0003-0735-4955)
- Karen H. Costenbader (ORCID: https://orcid.org/0000-0002-8972-9388)
- Yan Chen (ORCID: https://orcid.org/0000-0002-5317-1909)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Emory University (US)
- Grady Health System (US)
- Global College (CY)
- Durham VA Medical Center (US)
- Analysis Group (United States) (US)
Publication Details
- Journal
- Rheumatology and Therapy
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1007/s40744-025-00774-6
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00