Raman micro-spectroscopy reveals the metabolic alterations in primary prostate tumor tissues of patients with metastases
The CRM could be a potential tool for predicting metastases by analyzing prostate biopsy tissues at the time of diagnosis. Our study found that metabolic remodelling of primary tumors occurred during the metastasis process. The metabolic alterations in primary tumor tissue can help elucidate the underlying mechanisms of the metastasis process, leading to the development of new therapies.
Authors
- Xiaoguang Shao (ORCID: https://orcid.org/0000-0002-5570-8984)
- Hongyang Qian (ORCID: https://orcid.org/0000-0003-0560-1721)
- Qihan Zhang (ORCID: https://orcid.org/0009-0009-0212-4350)
- Jiahua Pan
- Shupeng Liu (ORCID: https://orcid.org/0000-0002-9276-7086)
- Wei Xue (ORCID: https://orcid.org/0000-0001-9298-9941)
- Heng Zhang (ORCID: https://orcid.org/0000-0002-4189-1351)
- Yinjie Zhu (ORCID: https://orcid.org/0009-0002-2937-210X)
- Bo Liu (ORCID: https://orcid.org/0009-0005-6182-8172)
Institutions
- Shanghai University (CN)
- Renji Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1186/s12967-025-06655-4
- Citations
- 4
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 6.54
Funders
- National Natural Science Foundation of China
- National Health Commission of the People's Republic of China