Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial

There was no significant effect from different doses of oxygen in a hyperbaric chamber. It is possible that the very modest improvements reported in other studies were due to a placebo effect. Claims that HBOT has a significant effect on Long COVID need further investigation before indiscriminately prescribing or promoting HBOT.

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Publication Details

Journal
Diving and Hyperbaric Medicine Journal
Published
2025-06-18
DOI
https://doi.org/10.28920/dhm55.2.104-113
Citations
1
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
1.39
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article

Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial

Costantino Balestra, Peter Germonpré, Nancy Stevens, Bert Rinia et al.
1 citations
Diving and Hyperbaric Medicine Journal
Long-Term Effects of COVID-19
1.39
article

Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial

Costantino Balestra, Peter Germonpré, Nancy Stevens, Bert Rinia, Leonard Caeyers, Leen D'hoore
article en
1 citations

Abstract

There was no significant effect from different doses of oxygen in a hyperbaric chamber. It is possible that the very modest improvements reported in other studies were due to a placebo effect. Claims that HBOT has a significant effect on Long COVID need further investigation before indiscriminately prescribing or promoting HBOT.

Diving and Hyperbaric Medicine JournalVol. 55(2)
Université Libre de Bruxelles (BE), European Centre for Ecotoxicology and Toxicology of Chemicals (BE), Queen Astrid Military Hospital (BE), Haute École de Bruxelles (BE)
Peace, Justice and strong institutions
Openalex Percentile: Top 19%
Long-Term Effects of COVID-19
1.39
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