Outcomes of Coronary Artery Bypass Surgery in Patients with Malignancy

Objective: In patients with severe coronary artery disease (CAD), the risk of tumor surgery under general anesthesia is high, and whether coronary revascularization should be prioritized remains debatable, considering tumor prognosis. We aimed to analyze surgical outcomes for severe CAD with malignancy. Materials and Methods: We analyzed 20 patients with malignant tumors and 256 who underwent coronary artery bypass graft surgery (CABG) at our hospital to investigate early and long-term outcomes. We also conducted propensity score analysis. Results: No significant differences were observed in preoperative background. Patients with malignancy had significantly fewer lesions and bypass grafts. There was no significance in postoperative complications or cardiac events. After propensity score matching, results were similar. Treatment for malignancy was performed safely post-CABG. However, two patients could not undergo scheduled treatment because of change in their clinical condition after CABG. Conclusion: CABG in patients with malignancy was safely performed and prevented postoperative cardiac events. Because postoperative status can be changeable, cancer team management should be considered for all CABG cases with malignancy.

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Publication Details

Journal
Open Journal of Thoracic Surgery
Published
2025-01-01
DOI
https://doi.org/10.4236/ojts.2025.152002
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
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article

Outcomes of Coronary Artery Bypass Surgery in Patients with Malignancy

Kayo Sugiyama, Katsuhiko Matsuyama, Masato Tochii, Hirotaka Watanuki
Open Journal of Thoracic Surgery
Chemotherapy-induced cardiotoxicity and mitigation
article

Outcomes of Coronary Artery Bypass Surgery in Patients with Malignancy

Kayo Sugiyama, Katsuhiko Matsuyama, Masato Tochii, Hirotaka Watanuki
article en

Abstract

Objective: In patients with severe coronary artery disease (CAD), the risk of tumor surgery under general anesthesia is high, and whether coronary revascularization should be prioritized remains debatable, considering tumor prognosis. We aimed to analyze surgical outcomes for severe CAD with malignancy. Materials and Methods: We analyzed 20 patients with malignant tumors and 256 who underwent coronary artery bypass graft surgery (CABG) at our hospital to investigate early and long-term outcomes. We also conducted propensity score analysis. Results: No significant differences were observed in preoperative background. Patients with malignancy had significantly fewer lesions and bypass grafts. There was no significance in postoperative complications or cardiac events. After propensity score matching, results were similar. Treatment for malignancy was performed safely post-CABG. However, two patients could not undergo scheduled treatment because of change in their clinical condition after CABG. Conclusion: CABG in patients with malignancy was safely performed and prevented postoperative cardiac events. Because postoperative status can be changeable, cancer team management should be considered for all CABG cases with malignancy.

Open Journal of Thoracic SurgeryVol. 15(02)
Aichi Medical University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 76%
Chemotherapy-induced cardiotoxicity and mitigation
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Outcomes of Coronary Artery Bypass Surgery in Patients with Malignancy — Kayo Sugiyama, Katsuhiko Matsuyama, et al. · Open Journal of Thoracic Surgery (2025) | TGRS Research Map | TGRS