Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda

HIV infection was significantly associated with an increased risk of congenital anomalies, while other obstetric and neonatal outcomes were similar between HIV-positive and HIV-negative women. We recommend enhanced prenatal monitoring and early fetal screening among HIV-positive pregnant women on dolutegravir-based ART. Additionally, prospective studies are needed to better understand the contribution of dolutegravir and maternal factors to congenital anomalies in HIV-exposed pregnancies.

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Publication Details

Journal
PLoS ONE
Published
2025-06-17
DOI
https://doi.org/10.1371/journal.pone.0326322
Citations
2
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
2.79
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article

Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda

James Okello, Jimmyy Opee, Daniel Ebbs, Felix Bongomin et al.
2 citations
PLoS ONE
HIV/AIDS Research and Interventions
2.79
article

Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda

James Okello, Jimmyy Opee, Daniel Ebbs, Felix Bongomin, Jolly Joe Lapat, Nixson Oyoo, Gloria Becky Labong, Christopher Wanican
article en
2 citations

Abstract

HIV infection was significantly associated with an increased risk of congenital anomalies, while other obstetric and neonatal outcomes were similar between HIV-positive and HIV-negative women. We recommend enhanced prenatal monitoring and early fetal screening among HIV-positive pregnant women on dolutegravir-based ART. Additionally, prospective studies are needed to better understand the contribution of dolutegravir and maternal factors to congenital anomalies in HIV-exposed pregnancies.

PLoS ONEVol. 20(6)
Gulu University (UG), Government General Hospital (IN), Yale University (US), Gulu Hospital (UG)
Good health and well-being
Openalex Percentile: Top 10%
HIV/AIDS Research and Interventions
2.79
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Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda — James Okello, Jimmyy Opee, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS