Obstetric and newborn outcomes of mothers with and without HIV infection in Anaka general hospital in Northern Uganda
HIV infection was significantly associated with an increased risk of congenital anomalies, while other obstetric and neonatal outcomes were similar between HIV-positive and HIV-negative women. We recommend enhanced prenatal monitoring and early fetal screening among HIV-positive pregnant women on dolutegravir-based ART. Additionally, prospective studies are needed to better understand the contribution of dolutegravir and maternal factors to congenital anomalies in HIV-exposed pregnancies.
Authors
- James Okello
- Jimmyy Opee (ORCID: https://orcid.org/0009-0001-3902-2712)
- Daniel Ebbs (ORCID: https://orcid.org/0000-0003-0426-0865)
- Felix Bongomin (ORCID: https://orcid.org/0000-0002-3268-0755)
- Jolly Joe Lapat (ORCID: https://orcid.org/0000-0001-9868-7565)
- Nixson Oyoo
- Gloria Becky Labong
- Christopher Wanican
Institutions
- Gulu University (UG)
- Government General Hospital (IN)
- Yale University (US)
- Gulu Hospital (UG)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1371/journal.pone.0326322
- Citations
- 2
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 2.79