Placental inflammation is increased in gestational diabetes mellitus: The role of inflammasome NLRP-3 and chemokine scavenger decoy receptor D6
GDM is characterized by higher serum levels of pro-inflammatory cytokines with consistent over-expression of the inflammasome NLRP-3 in placental tissues compared to normal pregnancy.
Authors
- Marianna Onori (ORCID: https://orcid.org/0000-0002-6790-4069)
- Giovanni Scambia (ORCID: https://orcid.org/0000-0002-9503-9041)
- Nicoletta Di Simone (ORCID: https://orcid.org/0000-0003-1273-3335)
- Caterina Policola (ORCID: https://orcid.org/0009-0005-1137-1098)
- Giuliana Beneduce (ORCID: https://orcid.org/0000-0003-3866-2109)
- Chiara Tersigni (ORCID: https://orcid.org/0000-0003-1590-3942)
- Vincenzo Arena (ORCID: https://orcid.org/0000-0002-4363-6311)
- Fabio Sannino
- Dario Pitocco (ORCID: https://orcid.org/0000-0002-6220-686X)
- Filomena Colella (ORCID: https://orcid.org/0000-0002-7088-6551)
- Donatella Lucchetti (ORCID: https://orcid.org/0000-0001-8147-0079)
- Alessandro Petrecca
- T. Ghi (ORCID: https://orcid.org/0000-0003-1823-1096)
- Alfredo Pontecorvi (ORCID: https://orcid.org/0000-0003-0570-6865)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Humanitas University (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1371/journal.pone.0326087
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00