Protein Structure Prediction Using CNN-Based Feature Extraction

Predicting protein structures is essential for understanding biological functions and advancing drug discovery. In this project, we developed a stacking-based model that integrates various machine learning techniques, including models like Support Vector Machines (SVM), Neural Networks (ANN), and Random Forests (RF) Feature extraction techniques were employed to identify key patterns in protein sequence data, enhancing the quality of inputs for the predictive models. By stacking these algorithms, we combined their strengths, resulting in improved prediction accuracy for protein structures. Our results show that the stacking-based approach significantly outperforms individual models, offering a more robust solution for challenging protein sequences.

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Publication Details

Published
2025-04-24
DOI
https://doi.org/10.1109/iccies63851.2025.11032318
Primary Topic
Machine Learning in Bioinformatics
Type
article
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article

Protein Structure Prediction Using CNN-Based Feature Extraction

Ahmad Raza, N. Anjali, Sourav Mondal, M. Sunitha Reddy et al.
Machine Learning in Bioinformatics
article

Protein Structure Prediction Using CNN-Based Feature Extraction

Ahmad Raza, N. Anjali, Sourav Mondal, M. Sunitha Reddy, Saranya Nayudu
article en

Abstract

Predicting protein structures is essential for understanding biological functions and advancing drug discovery. In this project, we developed a stacking-based model that integrates various machine learning techniques, including models like Support Vector Machines (SVM), Neural Networks (ANN), and Random Forests (RF) Feature extraction techniques were employed to identify key patterns in protein sequence data, enhancing the quality of inputs for the predictive models. By stacking these algorithms, we combined their strengths, resulting in improved prediction accuracy for protein structures. Our results show that the stacking-based approach significantly outperforms individual models, offering a more robust solution for challenging protein sequences.

Vignan's Foundation for Science, Technology & Research (IN)
Openalex Percentile: Top 87%
Machine Learning in Bioinformatics
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