Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low‐energy diet
Rapid and extensive hormonal changes occur after OS, but not LED, despite similar weight loss. Of note, few differences were seen in the fasting state, whereas multiple endocrine pathways were affected during the oral glucose challenge. The findings suggest altered responses to oral glucose after OS in several hypothalamus-pituitary endocrine axes and peripheral endocrine glands.
Authors
- Maria J. Pereira (ORCID: https://orcid.org/0000-0001-5498-3899)
- Håkan Åhlström (ORCID: https://orcid.org/0000-0002-8701-969X)
- Ulf Risérus (ORCID: https://orcid.org/0000-0002-8620-4586)
- Jan W. Eriksson (ORCID: https://orcid.org/0000-0002-2639-9481)
- Susanne Hetty (ORCID: https://orcid.org/0000-0002-0964-6700)
- Argyri Mathioudaki (ORCID: https://orcid.org/0000-0003-0200-0760)
- Magnus Sundbom (ORCID: https://orcid.org/0000-0002-6243-2859)
- Giovanni Fanni (ORCID: https://orcid.org/0000-0002-7920-8909)
- Joel Kullberg (ORCID: https://orcid.org/0000-0001-8205-7569)
- Fleur Hukema
Institutions
- Uppsala University (SE)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1111/dom.16526
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- AstraZeneca
- European Commission
- Hjärt-Lungfonden
- Novo Nordisk
- Vetenskapsrådet
- Akademiska Sjukhuset
- Stiftelsen Familjen Ernfors Fond
- Uppsala Universitet
- Agnes och Mac Rudbergs Stiftelse
- P. O. Zetterlings stiftelse
- Diabetesförbundet
- Novo Nordisk Fonden
- Horizon 2020 Framework Programme
- HORIZON EUROPE Framework Programme
- HORIZON EUROPE Marie Sklodowska-Curie Actions
- HORIZON EUROPE European Innovation Council