Flow Cytometric Assessment of <scp>TRBC1</scp> Expression for the Diagnosis of T‐Cell Lymphoma: Clinical Utility and Pitfalls Related to T‐Cell Clones of Uncertain Significance

This study demonstrates the clinical utility of flow cytometric TRBC1 assessment in diagnosing T-cell lymphomas, characterizing TRBC1 expression patterns, and identifying TCUS in a large cohort of specimens without T-cell lymphoma involvement across diverse clinical settings. Given the relatively frequent detection of TCUS, these findings underscore the importance of interpreting TRBC1 flow cytometry results within the appropriate clinical context.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2025-06-16
DOI
https://doi.org/10.1111/ijlh.14508
Citations
1
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.47

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article

Flow Cytometric Assessment of TRBC1 Expression for the Diagnosis of T‐Cell Lymphoma: Clinical Utility and Pitfalls Related to T‐Cell Clones of Uncertain Significance

Sang Eun Yoon, Boram Kim, Hee‐Jin Kim, Hyun‐Young Kim et al.
1 citations
International Journal of Laboratory Hematology
Lymphoma Diagnosis and Treatment
1.47
article

Flow Cytometric Assessment of TRBC1 Expression for the Diagnosis of T‐Cell Lymphoma: Clinical Utility and Pitfalls Related to T‐Cell Clones of Uncertain Significance

Sang Eun Yoon, Boram Kim, Hee‐Jin Kim, Hyun‐Young Kim, SooHo Yu
article en
1 citations

Abstract

This study demonstrates the clinical utility of flow cytometric TRBC1 assessment in diagnosing T-cell lymphomas, characterizing TRBC1 expression patterns, and identifying TCUS in a large cohort of specimens without T-cell lymphoma involvement across diverse clinical settings. Given the relatively frequent detection of TCUS, these findings underscore the importance of interpreting TRBC1 flow cytometry results within the appropriate clinical context.

International Journal of Laboratory HematologyVol. 47(5)
Samsung Medical Center (KR), Sungkyunkwan University (KR)
National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Reduced inequalities
Openalex Percentile: Top 18%
Lymphoma Diagnosis and Treatment
1.47
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