Fibrinogen time course in acute ischemic stroke patients treated with intravenous thrombolysis with alteplase or tenecteplase
Fibrinogen depletion was observed only in AIS patients receiving alteplase and was associated with numerically higher rates of major hemorrhagic complications. These findings require independent confirmation in larger, international cohort studies.
Authors
- Maria Chondrogianni (ORCID: https://orcid.org/0000-0002-8315-5846)
- Maria‐Ioanna Stefanou (ORCID: https://orcid.org/0000-0002-2305-6627)
- Georgios K. Tsivgoulis (ORCID: https://orcid.org/0000-0002-0640-3797)
- Aikaterini Theodorou (ORCID: https://orcid.org/0000-0001-7229-2610)
- Klearchos Psychogios (ORCID: https://orcid.org/0000-0003-3993-2545)
- Odysseas Kargiotis (ORCID: https://orcid.org/0000-0002-8317-6428)
- Lina Palaiodimou (ORCID: https://orcid.org/0000-0001-7757-609X)
- Effie Polyzogopoulou (ORCID: https://orcid.org/0000-0001-7585-1203)
- Apostolοs Safouris (ORCID: https://orcid.org/0000-0002-9630-6949)
- Guillaume Turc (ORCID: https://orcid.org/0000-0001-5059-4095)
- Andrei V. Alexandrov (ORCID: https://orcid.org/0000-0001-8871-1023)
- Frantzeska Frantzeskaki (ORCID: https://orcid.org/0000-0002-3897-6282)
- Marios Themistocleous (ORCID: https://orcid.org/0000-0003-3810-8001)
- Eleni Bakola (ORCID: https://orcid.org/0000-0002-7002-9795)
- Konstantinos Melanis
- Stella Fanouraki (ORCID: https://orcid.org/0009-0003-3496-7543)
- Georgios Magoufis
Institutions
- Inserm (FR)
- University of Tennessee Health Science Center (US)
- National and Kapodistrian University of Athens (GR)
- Université Paris Cité (FR)
- Banner Health (US)
- Banner - University Medical Center Phoenix (US)
- Children's Hospital Agia Sophia (GR)
- Banner - University Medical Center Tucson (US)
- University General Hospital Attikon (GR)
- Hertie Institute for Clinical Brain Research (DE)
- FHU Neurovasc (FR)
- Metropolitan Hospital (GR)
- University of Tübingen (DE)
Publication Details
- Journal
- European Stroke Journal
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1177/23969873251345387
- Citations
- 4
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 5.42