Case Report: Diagnosing and treating gallbladder neuroendocrine neoplasms through comparative analysis: a case series and literature review
GB-NENs are highly aggressive and associated with poor prognosis. We recommend: 1) Radical cholecystectomy as the primary treatment for resectable GB-NENs; 2) Platinum-based chemotherapy as the first-line regimen, with close monitoring for drug resistance; 3) Early assessment of chemosensitivity to guide further treatment decisions, postoperative chemotherapy combined with adjuvant therapies may improve surgical efficacy.
Authors
- Jiandong Li (ORCID: https://orcid.org/0000-0002-8851-836X)
- Yuxing Dong
- Jiayao Zhang (ORCID: https://orcid.org/0000-0002-9694-7404)
- Baochun Lu (ORCID: https://orcid.org/0000-0001-8350-0227)
Institutions
- Shaoxing People's Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fonc.2025.1606850
- Citations
- 1
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province