Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice

The SAL strain intervention significantly improved redox homeostasis, restored intestinal barrier integrity, and reversed gut dysbiosis, highlighting its dual regulatory role in anti-aging mechanisms. These findings demonstrate the potential of <i>L. plantarum</i> SAL as an anti-aging probiotic and establish a theoretical framework for microbiota - targeted interventions to alleviate age-related pathologies.