Necrotizing Dermatitis: Clinical and Pathogenetic Forms, Differ-Ential Diagnosis and Modern Approaches to Treatment

Necrotizing dermatitis is a heterogeneous group of skin lesions characterized by pro-gressive necrosis of the dermis and/or subcutaneous tissue against the background of infectious, autoimmune or vasculopathic genesis. This condition is associated with a high risk of systemic complications, disability and death, especially with untimely diagnosis and tactical errors in treatment. The article discusses modern clinical and pathogenetic forms of necrotizing dermati-tis, including necrotizing fasciitis, pyoderma gangrenous, necrotizing vasculitis and other rare syndromes. Particular attention is paid to the algorithms of differential diagnosis, the role of laboratory and imaging methods, as well as an interdisciplinary approach to treatment, taking into account the etiology of the disease. The review is based solely on English-language publi-cations of recent years and aims to summarize the most clinically relevant data for dermatolo-gists, surgeons, and intensive care professionals.