Instrument-supported gait analysis characterizes gait domain changes in patients with suspected normal pressure hydrocephalus
This study confirmed the clinical utility of the 20% gait velocity improvement criterion for differentiating responders and non-responders in a cohort of patients with mostly probable iNPH, in whom clinical parameters alone were insufficient for classification. Notably, instrument-supported gait analysis validated this criterion by providing a more comprehensive characterization of gait disturbances compared to the 10 m walk test. However, further-especially longitudinal-studies are needed to reveal the full potential of the instrument-supported gait analysis in patients with (early/probable) iNPH.
Authors
- Peter H. Weiss (ORCID: https://orcid.org/0000-0002-5230-9080)
- Gereon R. Fink (ORCID: https://orcid.org/0000-0002-8230-1856)
- Christian Grefkes (ORCID: https://orcid.org/0000-0002-1656-720X)
- Veronika Wunderle
- Carolin Semmler (ORCID: https://orcid.org/0000-0002-5784-0735)
- Oezguer A. Onur (ORCID: https://orcid.org/0000-0001-8336-7075)
- Michael T. Barbe (ORCID: https://orcid.org/0000-0003-1149-8054)
- Taylan D. Kuzu (ORCID: https://orcid.org/0000-0003-2146-2442)
Institutions
- Goethe University Frankfurt (DE)
- Forschungszentrum Jülich (DE)
- University of Cologne (DE)
- University Hospital Frankfurt (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Neurological Research and Practice
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1186/s42466-025-00394-z
- Citations
- 3
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 2.73
Funders
- Eli Lilly and Company
- Biogen
- Boston Scientific Corporation
- Deutsche Forschungsgemeinschaft
- Eisai
- Marga und Walter Boll-Stiftung
- Universitätsklinikum Köln
- Eisai Incorporated