Advanced Characterization of Vitreous Hyperreflective Dots via OCT-Derived Metrics: A Cross-Sectional Study
While vitreous inflammation scales must evolve toward more objective metrics, our findings suggest that VHDs on OCT can act as confounders, as they may represent normal vitreous cells or even the presence of vitreous degeneration. The reflectivity index appears to have better reproducibility than simple count; however, when searching for a more objective parameter for measuring vitreous inflammation, vitreous degeneration must be considered.
Authors
- William Rojas‐Carabali (ORCID: https://orcid.org/0000-0002-9976-8989)
- Carlos Cifuentes‐González (ORCID: https://orcid.org/0000-0002-2703-0977)
- Paola Saboya‐Galindo (ORCID: https://orcid.org/0009-0009-2159-2459)
- Jin Lin (ORCID: https://orcid.org/0000-0002-3709-8086)
- Rupesh Agrawal (ORCID: https://orcid.org/0000-0002-6662-5850)
- Joewee Boon
- Eunice Jin Hui Goh (ORCID: https://orcid.org/0000-0001-9970-5729)
Institutions
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Singapore National Eye Center (SG)
- Tan Tock Seng Hospital (SG)
- Singapore Eye Research Institute (SG)
- Duke-NUS Medical School (SG)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Ophthalmology and Therapy
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s40123-025-01182-3
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Medical Research Council