A Preliminary in vitro Investigation on the Crude Methanol Extract of Bacopa monnieri (L.) Pennell. An Important Multi Medicinal Plant

The present investigation is to study the B. monnieri crude methanol extract antibacterial and anticancer activities. Crude methanol extract showed very positive antibacterial activity on 6 different bacterial strains. Staphylococcus aureus has been identified as more sensitive than the other strains (Staphylococcus aureus>Enterococcus faecalis>Bacillus subtilis> Escherichia coli> Pseudomonas aeruginosa>Proteus vulgaris). Further, the crude methanol extract exhibited a promising anticancer activity and expressed considerable IC50 values (108.6 and 86.4μg/ml for MCF-7 and MDA-MB-231). These observations suggest that the medicinal plant B. monnieri can be used in antibacterial and anticancer studies.