Papillary and medullary thyroid carcinoma with a single hybrid lymph node: a case report with review of literature

Synchronous medullary and papillary thyroid carcinoma (MTC-PTC) is rare, particularly with metastasis to the same lymph node. This study presents a unique case of synchronous metastatic MTC and PTC in a single lymph node. A 35-year-old male presented with a neck swelling, diagnosed with MTC-PTC. Imaging revealed thyroid nodules, and histopathological examination following thyroidectomy confirmed mixed MTC-PTC with lymph node metastasis. Literature reports similar cases in patients aged 24-64, often presenting with neck lumps. Management typically involves total thyroidectomy with lymph node dissection, yielding favorable outcomes. Treatment should follow guidelines based on disease stage. Due to its rarity, further research is needed to better understand and manage this condition.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-05-31
DOI
https://doi.org/10.1093/jscr/rjaf389
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
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article

Papillary and medullary thyroid carcinoma with a single hybrid lymph node: a case report with review of literature

Aras J. Qaradakhy, Rawa M. Ali, Shaho F. Ahmed, Fahmi hussein Kakamad et al.
Journal of Surgical Case Reports
Thyroid Cancer Diagnosis and Treatment
article

Papillary and medullary thyroid carcinoma with a single hybrid lymph node: a case report with review of literature

Aras J. Qaradakhy, Rawa M. Ali, Shaho F. Ahmed, Fahmi hussein Kakamad, Abdulwahid M. Salih, Hiwa O. Abdullah, Aso S. Muhialdeen, Shko H. Hassan, Hardi Dhahir, Abdullah Abdulrahman Qadir
article en

Abstract

Synchronous medullary and papillary thyroid carcinoma (MTC-PTC) is rare, particularly with metastasis to the same lymph node. This study presents a unique case of synchronous metastatic MTC and PTC in a single lymph node. A 35-year-old male presented with a neck swelling, diagnosed with MTC-PTC. Imaging revealed thyroid nodules, and histopathological examination following thyroidectomy confirmed mixed MTC-PTC with lymph node metastasis. Literature reports similar cases in patients aged 24-64, often presenting with neck lumps. Management typically involves total thyroidectomy with lymph node dissection, yielding favorable outcomes. Treatment should follow guidelines based on disease stage. Due to its rarity, further research is needed to better understand and manage this condition.

Journal of Surgical Case ReportsVol. 2025(6)
University of Sulaimani (IQ)
Good health and well-being
Openalex Percentile: Top 79%
Thyroid Cancer Diagnosis and Treatment
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Papillary and medullary thyroid carcinoma with a single hybrid lymph node: a case report with review of literature — Aras J. Qaradakhy, Rawa M. Ali, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS