Barriers to guideline implementation in intermediate- and high-risk Pulmonary Embolism: insights from a real-world cohort study
Guideline-recommended thrombolysis is underutilized in high-risk PE, due to safety concerns and contra-indications. CBT demonstrates a promising alternative with a favourable safety profile and low mortality rates, highlighting the need for prospective studies. Multidisciplinary approaches, such as Pulmonary Embolism Response Teams, may help to standardize care and to improve outcomes.
Authors
- Christophe Vandenbriele (ORCID: https://orcid.org/0000-0001-5151-6400)
- Marc Vanderheyden (ORCID: https://orcid.org/0000-0003-3050-5221)
- Dan Schelfaut (ORCID: https://orcid.org/0000-0001-8262-333X)
- Monika Beles (ORCID: https://orcid.org/0000-0002-4229-783X)
- Eric Wyffels (ORCID: https://orcid.org/0000-0002-9906-4682)
- Michiel Meylaers (ORCID: https://orcid.org/0009-0008-9988-2432)
Institutions
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Imperial Valley College (US)
- Harefield Hospital (GB)
- Onze Lieve Vrouwziekenhuis Hospital (BE)
- Imperial College London (GB)
Publication Details
- Journal
- Acta Clinica Belgica
- Published
- 2025-05-04
- DOI
- https://doi.org/10.1080/17843286.2025.2519723
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00