Validation of the COTS Calculator for Tubercular Uveitis: Predictive Performance and Diagnostic Utility in an Indian Cohort
The COTS Calculator, particularly the M4I2 model, provides a useful clinical tool to guide ATT decisions in OTB. While limited in ruling out TB, its integration with radiological and immunological testing supports early treatment decisions in TB-endemic settings. Prospective validation is warranted.
Authors
- William Rojas‐Carabali (ORCID: https://orcid.org/0000-0002-9976-8989)
- Ludi Zhang (ORCID: https://orcid.org/0000-0003-2061-4563)
- Bernett Teck Kwong Lee (ORCID: https://orcid.org/0000-0002-2709-1972)
- Zheng Xian Thng (ORCID: https://orcid.org/0000-0003-3275-7537)
- Carlos Cifuentes‐González (ORCID: https://orcid.org/0000-0002-2703-0977)
- Gazal Patnaik
- Janakiraman Palani
- Jyotirmay Biswas
- Rupesh Agrawal
Institutions
- Sankara Nethralaya (IN)
- Nanyang Technological University (SG)
- Tan Tock Seng Hospital (SG)
- Singapore Eye Research Institute (SG)
- Duke-NUS Medical School (SG)
Publication Details
- Journal
- Ocular Immunology and Inflammation
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1080/09273948.2025.2517309
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Health
- National Medical Research Council