Pruritus in intrahepatic cholestasis of pregnancy: the role of substance p
The concentration of substance P is increased in patients with intrahepatic cholestasis of pregnancy and is correlated with the severity of the pruritus. While the precise role of elevated substance P levels in the etiology of intrahepatic cholestasis of pregnancy remains uncertain, it may contribute to the pathogenesis of pruritus through central and peripheral effects.
Authors
- Ümit Taşdemir (ORCID: https://orcid.org/0000-0001-9745-6327)
- Oya Demirci (ORCID: https://orcid.org/0000-0001-5578-4437)
- Ömer Gökhan Eyisoy (ORCID: https://orcid.org/0000-0003-0869-4660)
- Sinem Tekin (ORCID: https://orcid.org/0000-0003-4183-6472)
- Çağdaş Özgökçe (ORCID: https://orcid.org/0000-0003-4960-4625)
Institutions
- Zeynep Kamil Hospital (TR)
- Haseki Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
Publication Details
- Journal
- Revista da Associação Médica Brasileira
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1806-9282.20242025
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00