Immature granulocyte and neutrophil-to-lymphocyte ratio in acute appendicitis: new markers to strengthen diagnosis

Immature granulocyte count and neutrophil-to-lymphocyte ratio show a significant elevation in acute appendicitis, proving useful additions to traditional diagnostic tests. C-reactive protein is the most reliable indicator; however, immature granulocyte and neutrophil-to-lymphocyte ratio may prove useful in ambiguous situations, potentially decreasing dependence on imaging techniques. Prospective studies are warranted to validate these findings and explore their prognostic value in complicated appendicitis.