Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats

Liquiritin is capable of inhibiting neuronal apoptosis in the hippocampus of PSD rats to improve depression symptoms. This improvement may be achieved by reducing the expression of Bax and increasing the expressions of Bcl-2 and BDNF in the hippocampus of PSD rats.

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Publication Details

Journal
Cerebral Circulation - Cognition and Behavior
Published
2025-01-01
DOI
https://doi.org/10.1016/j.cccb.2025.100388
Primary Topic
Pharmacological Effects of Natural Compounds
Type
article
Field-Weighted Citation Impact
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article

Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats

Dan Dai, Ganglin Yan, Fumin Zhang, Yun Li et al.
Cerebral Circulation - Cognition and Behavior
Pharmacological Effects of Natural Compounds
article

Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats

Dan Dai, Ganglin Yan, Fumin Zhang, Yun Li, Qiang Zi
article en

Abstract

Liquiritin is capable of inhibiting neuronal apoptosis in the hippocampus of PSD rats to improve depression symptoms. This improvement may be achieved by reducing the expression of Bax and increasing the expressions of Bcl-2 and BDNF in the hippocampus of PSD rats.

Cerebral Circulation - Cognition and BehaviorVol. 9
Soochow University (CN), Changshu No.1 People's Hospital (CN), Baoshan University (CN), Dali University (CN)
Zero hunger
Openalex Percentile: Top 82%
Pharmacological Effects of Natural Compounds
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Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats — Dan Dai, Ganglin Yan, et al. · Cerebral Circulation - Cognition and Behavior (2025) | TGRS Research Map | TGRS