Association Between Orthostatic Intolerance Symptoms and Cognitive Complaints in Hypermobile Ehlers-Danlos Syndrome (hEDS) and Joint Hypermobility Spectrum Disorder (JHSD): A Cross-Sectional Analysis
The researchers found a statistically significant yet low level of association between OI and cognitive complaints in individuals with hEDS and JHSD. These results suggest that autonomic dysfunction may play a role in the cognitive symptoms experienced by this group of individuals. Future objective assessment studies should be conducted to better understand the mechanisms involved and the contributions of psychological and emotional factors.
Authors
- Anam Tariq (ORCID: https://orcid.org/0000-0002-5564-1935)
- Shivam Singla
- Allah Rakhio Jamali (ORCID: https://orcid.org/0000-0002-5607-1495)
- Marium Nadeem Khan (ORCID: https://orcid.org/0000-0001-5710-7421)
- Syed Imran
- Mohammad K. A. Basra
- Hammad Khalid Malik
- Aakash Mahato
- Uzma Asmat
- Zainab Mohsin
- Imran K Mirani
Institutions
- Liaquat University of Medical & Health Sciences (PK)
- CMH Lahore Medical College and Institute of Dentistry (PK)
- Jinnah Sindh Medical University (PK)
- Shifa International Hospital (PK)
- University College of Islamabad (PK)
Publication Details
- Journal
- Cureus
- Published
- 2025-06-16
- DOI
- https://doi.org/10.7759/cureus.86123
- Citations
- 1
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 1.82