Cost-Effectiveness of S-Adenosyl-L-Methionine for Intrahepatic Cholestasis in the United Arab Emirates
SAMe demonstrates cost-effectiveness compared to UDCA and no treatment for chronic IHC in the UAE, particularly when considering its broader impact on comorbidities. These findings support the integration of SAMe into treatment protocols for IHC, potentially improving patient outcomes and optimizing healthcare resource allocation. Further research is needed to address data gaps, especially regarding UDCA's effects on jaundice and depressed mood in IHC.
Authors
- Kaiser Raja (ORCID: https://orcid.org/0009-0003-3134-2601)
- Ahmad Nader Fasseeh (ORCID: https://orcid.org/0000-0001-9878-7734)
- Nasr Fawzy Nasr (ORCID: https://orcid.org/0000-0003-1583-9231)
- Ahmed M. Rasmy
- Ahmad Jazzar
- Ahmed Gomaa
- Omar N Fasseeh
Institutions
- Middle East Institute (US)
- Abu Dhabi Department of Education and Knowledge (AE)
- Abbott (United Kingdom) (GB)
- King's College Hospital (GB)
- Dubai Medical College (AE)
- Alexandria University (EG)
Publication Details
- Journal
- Cureus
- Published
- 2025-06-16
- DOI
- https://doi.org/10.7759/cureus.86124
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00