Chronic non-healing ulcer reveals pyoderma gangrenosum: A case report

Pyoderma gangrenosum is a rare, ulcerative skin condition with complex diagnostic and therapeutic challenges, particularly in cases without associated systemic conditions. We present the case of a 71-year-old female with a chronic, non-healing ulcer, initially unresponsive to conventional topical treatments. After a thorough evaluation and biopsy, a diagnosis of pyoderma gangrenosum was made. Treatment efforts included both intralesional and topical therapies, with varying responses observed. This case highlights the challenges in diagnosing and managing pyoderma gangrenosum, emphasizing the need for individualized care and a multidisciplinary approach to treat chronic, non-healing ulcers.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-06-16
DOI
https://doi.org/10.1177/2050313x251350372
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

Chronic non-healing ulcer reveals pyoderma gangrenosum: A case report

Philip Doiron, Robyn Evans, Orhan Yilmaz
SAGE Open Medical Case Reports
Autoimmune and Inflammatory Disorders
article

Chronic non-healing ulcer reveals pyoderma gangrenosum: A case report

Philip Doiron, Robyn Evans, Orhan Yilmaz
article en

Abstract

Pyoderma gangrenosum is a rare, ulcerative skin condition with complex diagnostic and therapeutic challenges, particularly in cases without associated systemic conditions. We present the case of a 71-year-old female with a chronic, non-healing ulcer, initially unresponsive to conventional topical treatments. After a thorough evaluation and biopsy, a diagnosis of pyoderma gangrenosum was made. Treatment efforts included both intralesional and topical therapies, with varying responses observed. This case highlights the challenges in diagnosing and managing pyoderma gangrenosum, emphasizing the need for individualized care and a multidisciplinary approach to treat chronic, non-healing ulcers.

SAGE Open Medical Case ReportsVol. 13
University of Toronto (CA), Women's College Hospital (CA), University of Saskatchewan (CA)
Good health and well-being
Openalex Percentile: Top 80%
Autoimmune and Inflammatory Disorders
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Chronic non-healing ulcer reveals pyoderma gangrenosum: A case report — Philip Doiron, Robyn Evans, et al. · SAGE Open Medical Case Reports (2025) | TGRS Research Map | TGRS