Psychiatric adverse events linked to glucagon-like peptide 1 analogues: a disproportionality analysis in American, Canadian and Australian adverse event databases
GLP-1 analogues, particularly semaglutide and liraglutide, are associated with significant psychiatric AEs, especially depression and suicidal ideation. Further studies are required to understand the mechanisms underlying these associations, particularly in patients with pre-existing psychiatric conditions.
Authors
- Chiao Xin Lim (ORCID: https://orcid.org/0000-0001-5543-8411)
- D. Lynn Morris
- Vijayaprakash Suppiah (ORCID: https://orcid.org/0000-0001-5496-935X)
- Sihua Liang (ORCID: https://orcid.org/0000-0001-7651-169X)
- Jonah Katranski
Institutions
- University of South Australia (AU)
- SA Health (AU)
- Monash University (AU)
- RMIT University (AU)
Publication Details
- Journal
- International Journal of Clinical Pharmacy
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s11096-025-01943-x
- Citations
- 4
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 5.23