Brugada Phenocopy in a Critical Obstetric Patient: A Case Report

Brugada phenocopy (BrP) is an electrocardiographic (ECG) alteration that mimics Brugada syndrome (BrS) but lacks the associated genetic predisposition. It manifests as a transient pattern induced by reversible factors such as electrolyte imbalances, internal environment disturbances, and the use of certain drugs. In critically ill patients, hyperkalemia and acidosis are common triggers of this phenomenon, affecting ventricular repolarization and generating an ECG pattern identical to BrS. This report describes the case of a 30-year-old female patient who, following a complicated cesarean section with hemorrhagic shock, developed BrP induced by hyperkalemia and metabolic acidosis. The patient initially exhibited a type 1 Brugada ECG pattern, which evolved into a type 2 pattern and ultimately normalized after correction of the underlying disorders through hemodialysis. This case highlights the importance of an accurate differential diagnosis, as misidentifying BrP as true BrS could lead to inappropriate interventions, such as the implantation of defibrillators.

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Journal
Case Reports in Medicine
Published
2025-01-01
DOI
https://doi.org/10.1155/carm/9972483
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
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article

Brugada Phenocopy in a Critical Obstetric Patient: A Case Report

Annia de la Caridad Aguirre Ruiz, M.J. García, Yassel Arias Otamendy
Case Reports in Medicine
Cardiac electrophysiology and arrhythmias
article

Brugada Phenocopy in a Critical Obstetric Patient: A Case Report

Annia de la Caridad Aguirre Ruiz, M.J. García, Yassel Arias Otamendy
article en

Abstract

Brugada phenocopy (BrP) is an electrocardiographic (ECG) alteration that mimics Brugada syndrome (BrS) but lacks the associated genetic predisposition. It manifests as a transient pattern induced by reversible factors such as electrolyte imbalances, internal environment disturbances, and the use of certain drugs. In critically ill patients, hyperkalemia and acidosis are common triggers of this phenomenon, affecting ventricular repolarization and generating an ECG pattern identical to BrS. This report describes the case of a 30-year-old female patient who, following a complicated cesarean section with hemorrhagic shock, developed BrP induced by hyperkalemia and metabolic acidosis. The patient initially exhibited a type 1 Brugada ECG pattern, which evolved into a type 2 pattern and ultimately normalized after correction of the underlying disorders through hemodialysis. This case highlights the importance of an accurate differential diagnosis, as misidentifying BrP as true BrS could lead to inappropriate interventions, such as the implantation of defibrillators.

Case Reports in MedicineVol. 2025(1)
University of Havana (CU), Cuban Neuroscience Center (CU), Colorado Latino Leadership, Advocacy & Research Organization (US), Universidad de Guantánamo (CU)
Openalex Percentile: Top 76%
Cardiac electrophysiology and arrhythmias
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