Topical JAK inhibitor for refractory skin inflammation in STAT1 GOF
Topical ruxolitinib induced rapid and sustained improvement of refractory skin inflammation in a child with STAT1 GOF disease, highlighting its potential in managing localized inflammation in immune dysregulation.
Authors
- Claire Booth (ORCID: https://orcid.org/0000-0002-2626-5037)
- Valentina Guarnieri (ORCID: https://orcid.org/0000-0002-5578-7002)
- Tiphaine Arlabosse (ORCID: https://orcid.org/0000-0002-2029-0733)
- Gabriela Petrof (ORCID: https://orcid.org/0000-0001-8113-0373)
Institutions
- Great Ormond Street Hospital (GB)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Department of Medical Sciences (BY)
- University of Florence (IT)
- University College London (GB)
Publication Details
- Journal
- Journal of Human Immunity
- Published
- 2025-05-29
- DOI
- https://doi.org/10.70962/jhi.20250049
- Citations
- 1
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.80