Leveraging genetic data for female breast cancer prevention and therapy: Perspectives from Mendelian randomization
Leveraging genome-wide association studies, Mendelian randomization analysis has been applied to explore the potential causal associations between various risk factors and female breast cancer, predict the efficacy and adverse effects of pre-existing and new-onset drugs, and evaluate opportunities of drug repurposing for the therapy of female breast cancer.
Authors
- Jinhui Tian (ORCID: https://orcid.org/0000-0002-7082-3569)
- Wenbo Meng (ORCID: https://orcid.org/0000-0002-9355-0225)
- Danqi Huang
- Jiang Li (ORCID: https://orcid.org/0000-0001-8244-0349)
- Shengling Qin (ORCID: https://orcid.org/0009-0003-2068-6628)
- Wei Xiong (ORCID: https://orcid.org/0000-0003-2126-8535)
- Jianping Huang (ORCID: https://orcid.org/0000-0003-2845-797X)
- Yang Bai (ORCID: https://orcid.org/0000-0002-6991-9010)
- Quan Wang (ORCID: https://orcid.org/0000-0002-2821-5017)
- Jingbo Zhai (ORCID: https://orcid.org/0000-0001-8793-3628)
- Jinyi Liu (ORCID: https://orcid.org/0000-0003-1803-7752)
- Bobo Zheng (ORCID: https://orcid.org/0000-0003-1908-6484)
- Jinqiu Yuan (ORCID: https://orcid.org/0000-0002-7947-2646)
- Min Yang (ORCID: https://orcid.org/0000-0002-6836-3137)
- Huilin Wang (ORCID: https://orcid.org/0000-0002-4301-3077)
- Rui Sun (ORCID: https://orcid.org/0000-0001-7800-5459)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Shanxi Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- National Cancer Center (US)
- Shaanxi Provincial People's Hospital (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Lanzhou University Second Hospital (CN)
- Xijing Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- iMetaOmics.
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1002/imo2.70032
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Servier