Digital Pathology Quantification of the Continuum of Cirrhosis Severity in Human Liver Biopsies
Phenotypic digital pathology biomarkers provide robust, continuous measures of fibrosis severity and activity. They enhance traditional staging systems by offering improved resolution and reduced sensitivity to biopsy variability, with potential value in cirrhosis sub-staging and clinical decision-making.
Authors
- Mathieu Petitjean (ORCID: https://orcid.org/0000-0003-3468-7114)
- M. Isabel Fiel
- Thomas D. Schiano (ORCID: https://orcid.org/0000-0003-1878-5101)
- Louis Petitjean (ORCID: https://orcid.org/0000-0002-9223-5100)
- Arun Jayant Sanyal (ORCID: https://orcid.org/0000-0001-8682-5748)
- Xiaofei Zhang (ORCID: https://orcid.org/0000-0003-4516-9179)
- Li Chen (ORCID: https://orcid.org/0000-0001-8492-1963)
Institutions
- Long Island University (US)
- Virginia Commonwealth University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Liver International
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1111/liv.70166
- Citations
- 4
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.42