Humidity-Resistant Pt/CrVN<sub>2</sub> Fuel Cell Sensor for H<sub>2</sub>S Biomarker Detection
Real-time, remote monitoring of human biomarkers is essential for personalized medical diagnostics. Hydrogen sulfide (H<sub>2</sub>S), a key endogenous gas, serves as a crucial biomarker for conditions such as oral diseases. However, accurately detecting ppb-level H<sub>2</sub>S in high-humidity environments remains a challenge. Herein, we develop a Pt-loaded CrVN<sub>2</sub> fuel cell-type H<sub>2</sub>S sensor that exhibits high humidity resistance, ultralow detection limits (50 ppb), rapid response (4 s), and exceptional selectivity. The stable electronic structure of CrVN<sub>2</sub> ensures a consistent response across a wide relative humidity range (9%-79%). Furthermore, a wireless detection system incorporating the Pt/CrVN<sub>2</sub> sensor was designed and validated for breath diagnosis, demonstrating its practical application in smart healthcare. This study highlights the potential of Pt/CrVN<sub>2</sub> sensor as a promising platform for real-time, sensitive biomarker detection, contributing to the advancement of next-generation medical diagnostics.
Authors
- Yuxia Shan
- Jinkui Chu (ORCID: https://orcid.org/0000-0001-5742-8460)
- Minghui Yang (ORCID: https://orcid.org/0000-0003-1071-1327)
- Yu Liang (ORCID: https://orcid.org/0000-0002-4802-4189)
- Zhaorui Zhang (ORCID: https://orcid.org/0000-0001-6878-8816)
- Chonghui Zhu
Institutions
- Dalian Medical University (CN)
- Dalian University of Technology (CN)
- Faculty (United Kingdom) (GB)
Publication Details
- Journal
- ACS Sensors
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1021/acssensors.5c01358
- Primary Topic
- Gas Sensing Nanomaterials and Sensors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities