Osteoradionecrosis of the jaw: review of its aetiology, prevention and management
This review investigates osteoradionecrosis (ORN), a debilitating complication of head and neck radiotherapy. It explores its aetiology, prevention and diverse management approaches. High-dose radiotherapy (≥70 cGy) and tooth extractions in irradiated areas increase ORN risk. Diagnosis involves clinical presentation, imaging using OPT, CT and MRI, and biopsy. Management ranges from conservative measures to surgery (such as sequestrectomy and reconstruction). Understanding ORN is vital to minimize its occurrence and optimize patient outcomes through preventive measures and appropriate treatment strategies. CPD/Clinical Relevance: ORN is a significant complication of head and neck radiotherapy, requiring a multidisciplinary approach for prevention, accurate diagnosis, and effective management to optimize patient outcomes.
Authors
- Faris M Alabeedi (ORCID: https://orcid.org/0000-0002-1608-2245)
- Raunaq Shah
- Faisal A. Alzahrani (ORCID: https://orcid.org/0000-0003-0441-4000)
- Farya Domah (ORCID: https://orcid.org/0000-0002-8347-082X)
- Salvatore Luca La Terra
Institutions
- University of Ulster (GB)
- Najran University (SA)
Publication Details
- Journal
- Dental Update
- Published
- 2025-06-02
- DOI
- https://doi.org/10.12968/denu.2025.52.6.400
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00