Osteoradionecrosis of the jaw: review of its aetiology, prevention and management

This review investigates osteoradionecrosis (ORN), a debilitating complication of head and neck radiotherapy. It explores its aetiology, prevention and diverse management approaches. High-dose radiotherapy (≥70 cGy) and tooth extractions in irradiated areas increase ORN risk. Diagnosis involves clinical presentation, imaging using OPT, CT and MRI, and biopsy. Management ranges from conservative measures to surgery (such as sequestrectomy and reconstruction). Understanding ORN is vital to minimize its occurrence and optimize patient outcomes through preventive measures and appropriate treatment strategies. CPD/Clinical Relevance: ORN is a significant complication of head and neck radiotherapy, requiring a multidisciplinary approach for prevention, accurate diagnosis, and effective management to optimize patient outcomes.

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Journal
Dental Update
Published
2025-06-02
DOI
https://doi.org/10.12968/denu.2025.52.6.400
Primary Topic
Oral health in cancer treatment
Type
article
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article

Osteoradionecrosis of the jaw: review of its aetiology, prevention and management

Faris M Alabeedi, Raunaq Shah, Faisal A. Alzahrani, Farya Domah et al.
1 links
Dental Update
Oral health in cancer treatment
article

Osteoradionecrosis of the jaw: review of its aetiology, prevention and management

Faris M Alabeedi, Raunaq Shah, Faisal A. Alzahrani, Farya Domah, Salvatore Luca La Terra
article en

Abstract

This review investigates osteoradionecrosis (ORN), a debilitating complication of head and neck radiotherapy. It explores its aetiology, prevention and diverse management approaches. High-dose radiotherapy (≥70 cGy) and tooth extractions in irradiated areas increase ORN risk. Diagnosis involves clinical presentation, imaging using OPT, CT and MRI, and biopsy. Management ranges from conservative measures to surgery (such as sequestrectomy and reconstruction). Understanding ORN is vital to minimize its occurrence and optimize patient outcomes through preventive measures and appropriate treatment strategies. CPD/Clinical Relevance: ORN is a significant complication of head and neck radiotherapy, requiring a multidisciplinary approach for prevention, accurate diagnosis, and effective management to optimize patient outcomes.

Dental UpdateVol. 52(6)
University of Ulster (GB), Najran University (SA)
Good health and well-being
Openalex Percentile: Top 77%
Oral health in cancer treatment
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Osteoradionecrosis of the jaw: review of its aetiology, prevention and management — Faris M Alabeedi, Raunaq Shah, et al. · Dental Update (2025) | TGRS Research Map | TGRS