The indispensable role of Mediator complex subunit 27 during neurodevelopment
Our findings establish med27 as a critical gene of embryogenesis and neurogenesis, shedding light on the disease mechanism underlying MED27-associated NDDs.
Authors
- Yong Lei (ORCID: https://orcid.org/0000-0003-4864-7017)
- Shen Gu (ORCID: https://orcid.org/0000-0003-3107-1218)
- Xiaocheng Li (ORCID: https://orcid.org/0009-0005-9269-3987)
- Hui Zhao (ORCID: https://orcid.org/0000-0002-0731-7188)
- Tianyu Guo (ORCID: https://orcid.org/0000-0002-5108-5484)
- Nuermila Yiliyaer
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Chinese University of Hong Kong (HK)
- GfK (United States) (US)
- HKUST Shenzhen Research Institute (CN)
- Chinese University of Hong Kong, Shenzhen (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1186/s13578-025-01425-7
- Citations
- 4
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- Chinese University of Hong Kong
- Food and Health Bureau
- Guangdong Provincial Pearl River Talents Program
- Health and Medical Research Fund
- Science and Technology Planning Project of Guangdong Province
- Shenzhen Science and Technology Innovation Program