Evaluation of Maropitant‐Induced Changes in the Electrocardiogram of Healthy Dogs and Comparison of Three Methods for QT Interval Correction

Maropitant administered subcutaneously at a standard antiemetic dose may induce a slight prolongation of the QTc and a reduction in P wave amplitude that are unlikely to promote tachyarrhythmias such as torsades de pointes or become clinically relevant in healthy dogs. The Van de Water formula may be more accurate across a wide range of HRs in dogs than the Rautaharju and Hodges formulas.