Beta-Catenin Positive Giant Cell Tumor of Bone with Pathological Fracture Treated with Neoadjuvant Denosumab Therapy for Visualizing Extraskeletal Lesions

Neoadjuvant denosumab therapy is an effective approach for managing β-catenin positive GCTB with pathological fractures as it promotes intratumoral ossification and facilitates complete resection of GCTB, including extraskeletal lesions.

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Publication Details

Journal
Case Reports in Oncology
Published
2025-06-16
DOI
https://doi.org/10.1159/000546985
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
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article

Beta-Catenin Positive Giant Cell Tumor of Bone with Pathological Fracture Treated with Neoadjuvant Denosumab Therapy for Visualizing Extraskeletal Lesions

Yoichi Kaneuchi, Michiyuki Hakozaki, Shunsuke Sato, Takuya Nikaido et al.
1 links
Case Reports in Oncology
Bone Tumor Diagnosis and Treatments
article

Beta-Catenin Positive Giant Cell Tumor of Bone with Pathological Fracture Treated with Neoadjuvant Denosumab Therapy for Visualizing Extraskeletal Lesions

Yoichi Kaneuchi, Michiyuki Hakozaki, Shunsuke Sato, Takuya Nikaido, Yoshihiro Matsumoto, Shoki Yamada, Osamu Hasegawa, Itaru Ogawa, Takeo Suzuki
article en

Abstract

Neoadjuvant denosumab therapy is an effective approach for managing β-catenin positive GCTB with pathological fractures as it promotes intratumoral ossification and facilitates complete resection of GCTB, including extraskeletal lesions.

Case Reports in OncologyVol. 18(1)
Fukushima Medical University (JP)
Good health and well-being
Openalex Percentile: Top 79%
Bone Tumor Diagnosis and Treatments
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Beta-Catenin Positive Giant Cell Tumor of Bone with Pathological Fracture Treated with Neoadjuvant Denosumab Therapy for Visualizing Extraskeletal Lesions — Yoichi Kaneuchi, Michiyuki Hakozaki, et al. · Case Reports in Oncology (2025) | TGRS Research Map | TGRS