Gastric Mucormycosis in a Critically Ill Patient Who Survived Without Surgery: A Case Report

Gastrointestinal mucormycosis is an extremely rare but highly fatal manifestation of invasive fungal infections. We report a case of a 57-year-old man with preexisting type 2 diabetes mellitus who was admitted for diabetic ketoacidosis and acute hypoxic respiratory failure with a stay in the intensive care unit. The patient was found to be anemic. On further workup, he was found to have gastric mucormycosis. Despite the very high mortality rate, the patient showed remarkable improvement with antifungal therapy and supportive care. No surgery was performed as the patient refused surgical intervention. This rare case points to the need for high suspicion, timely biopsy, and quick intervention to have favorable outcomes.

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Publication Details

Journal
Cureus
Published
2025-06-16
DOI
https://doi.org/10.7759/cureus.86140
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

Gastric Mucormycosis in a Critically Ill Patient Who Survived Without Surgery: A Case Report

James R. Pellegrini, Shweta Chaudhary, Andrej M Sodoma, Steven J. Allen et al.
Cureus
Antifungal resistance and susceptibility
article

Gastric Mucormycosis in a Critically Ill Patient Who Survived Without Surgery: A Case Report

James R. Pellegrini, Shweta Chaudhary, Andrej M Sodoma, Steven J. Allen, Atieh D Ashkezari
article en

Abstract

Gastrointestinal mucormycosis is an extremely rare but highly fatal manifestation of invasive fungal infections. We report a case of a 57-year-old man with preexisting type 2 diabetes mellitus who was admitted for diabetic ketoacidosis and acute hypoxic respiratory failure with a stay in the intensive care unit. The patient was found to be anemic. On further workup, he was found to have gastric mucormycosis. Despite the very high mortality rate, the patient showed remarkable improvement with antifungal therapy and supportive care. No surgery was performed as the patient refused surgical intervention. This rare case points to the need for high suspicion, timely biopsy, and quick intervention to have favorable outcomes.

CureusVol. 17(6)
Nassau University Medical Center (US), New York Institute of Technology (US)
Openalex Percentile: Top 82%
Antifungal resistance and susceptibility
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