The impact of inflammatory markers on clinical outcomes in acute ischemic stroke patients following mechanical thrombectomy: A multicentre study
This study highlights the 24-h NLR as a powerful predictor of stroke outcomes post-MT, with a threshold of 4.30 strongly associated with poor prognosis. These findings suggest that NLR can guide personalized treatment approaches to improve recovery trajectories.
Authors
- Fahad Sheikh
- Domenico Maisano (ORCID: https://orcid.org/0000-0002-1221-9320)
- Lucio D’Anna (ORCID: https://orcid.org/0000-0002-4349-3322)
- Liqun Zhang (ORCID: https://orcid.org/0000-0001-6983-7915)
- Paolo Manganotti (ORCID: https://orcid.org/0000-0001-5305-6268)
- Caterina Del Regno
- Francesco Toraldo (ORCID: https://orcid.org/0009-0001-0076-193X)
- Giovanni Merlino (ORCID: https://orcid.org/0000-0002-1469-7860)
- Paresh Malhotra (ORCID: https://orcid.org/0000-0002-1897-0780)
- Mohamad K. Abdalkader (ORCID: https://orcid.org/0000-0002-9528-301X)
- Mariarosaria Valente (ORCID: https://orcid.org/0000-0001-6077-1315)
- Soma Banerjee (ORCID: https://orcid.org/0000-0003-2466-2909)
- Simona Sacco (ORCID: https://orcid.org/0000-0003-0651-1939)
- Matteo Foschi (ORCID: https://orcid.org/0000-0002-0321-7155)
- Raffaele Ornello (ORCID: https://orcid.org/0000-0001-9501-4031)
- Viva Levee
- Kyriakos Lobotesis (ORCID: https://orcid.org/0000-0001-5093-9751)
- Piers Klein (ORCID: https://orcid.org/0000-0001-7468-137X)
- Gian Luigi Gigli (ORCID: https://orcid.org/0000-0003-3526-1414)
- Hamza Zahid
- Gabriele Prandin (ORCID: https://orcid.org/0000-0002-5698-4737)
- Feras Fayez (ORCID: https://orcid.org/0009-0001-0103-9500)
- Thanh N. Nguyen
- Katherine Chulack
- Filippo Komauli
- Hakam Al-Karadsheh
- EdoardoPirera
- Adelaida Gartner Jarmillo
Institutions
- Boston Medical Center (US)
- University of Udine (IT)
- University of Trieste (IT)
- St George's, University of London (GB)
- University of L'Aquila (IT)
- Charing Cross Hospital (GB)
- Imperial College London (GB)
- University of Palermo (IT)
Publication Details
- Journal
- Journal of the Neurological Sciences
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1016/j.jns.2025.123587
- Citations
- 5
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- Imperial College London
- Imperial College Healthcare NHS Trust