Uncovering the impact of randomness in HIV hotspot formation: A mathematical modeling study

Early random fluctuations contribute to the emergence and persistence of prevalence outliers, especially in smaller communities. Recognizing the role of randomness in prevalence outlier formation in these settings is crucial for refining HIV control strategies, as traditional methods may overlook these areas. Adaptive surveillance systems can enhance detection and intervention efforts for HIV and future pandemics.

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Publication Details

Journal
PLoS Computational Biology
Published
2025-06-16
DOI
https://doi.org/10.1371/journal.pcbi.1013178
Primary Topic
HIV, Drug Use, Sexual Risk
Type
article
Field-Weighted Citation Impact
0.00
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article

Uncovering the impact of randomness in HIV hotspot formation: A mathematical modeling study

Samuel Mwalili, Diego F. Cuadros, Duncan Kioi Gathungu, Nao Yamamoto et al.
PLoS Computational Biology
HIV, Drug Use, Sexual Risk
article

Uncovering the impact of randomness in HIV hotspot formation: A mathematical modeling study

Samuel Mwalili, Diego F. Cuadros, Duncan Kioi Gathungu, Nao Yamamoto, Anna Bershteyn, Daniel Citron
article en

Abstract

Early random fluctuations contribute to the emergence and persistence of prevalence outliers, especially in smaller communities. Recognizing the role of randomness in prevalence outlier formation in these settings is crucial for refining HIV control strategies, as traditional methods may overlook these areas. Adaptive surveillance systems can enhance detection and intervention efforts for HIV and future pandemics.

PLoS Computational BiologyVol. 21(6)
Strathmore University (KE), Jomo Kenyatta University of Agriculture and Technology (KE), Digital Science (United States) (US), New York University (US)
Good health and well-being
Openalex Percentile: Top 80%
HIV, Drug Use, Sexual Risk
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Uncovering the impact of randomness in HIV hotspot formation: A mathematical modeling study — Samuel Mwalili, Diego F. Cuadros, et al. · PLoS Computational Biology (2025) | TGRS Research Map | TGRS